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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INSRR All Species: 22.73
Human Site: S1258 Identified Species: 55.56
UniProt: P14616 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14616 NP_055030.1 1297 143720 S1258 R P S F R L L S F Y Y S P E C
Chimpanzee Pan troglodytes Q5IS37 825 92786 D787 V C P K E V Y D V M L G C W Q
Rhesus Macaque Macaca mulatta XP_001100407 1367 154946 S1278 E P G F R E V S F Y Y S E E N
Dog Lupus familis XP_547526 1300 144046 S1258 R P S F R L F S F Y Y S P E C
Cat Felis silvestris
Mouse Mus musculus Q9WTL4 1300 144727 S1258 R P S F R L C S F Y Y S P E C
Rat Rattus norvegicus P24062 1370 155377 S1279 E P S F Q E V S F Y Y S E E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P08941 2311 260942 Y2244 H S P L C F S Y F L G D K E S
Frog Xenopus laevis O73798 1358 153845 S1274 D P G F K E V S F F Y S E E N
Zebra Danio Brachydanio rerio NP_694500 1405 158428 S1276 E P P F R E V S F F Y S E E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P09208 2144 239757 T1915 T S S N T N L T S H P V A M G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.2 54.2 92.3 N.A. 88.8 54.2 N.A. N.A. 21.2 52.6 50.8 N.A. 26 N.A. N.A. N.A.
Protein Similarity: 100 37.1 69.1 95.4 N.A. 92.7 68.9 N.A. N.A. 33.4 67.6 65.1 N.A. 36.6 N.A. N.A. N.A.
P-Site Identity: 100 0 60 93.3 N.A. 93.3 60 N.A. N.A. 13.3 46.6 53.3 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 6.6 66.6 93.3 N.A. 93.3 73.3 N.A. N.A. 13.3 66.6 66.6 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 10 0 0 10 0 10 0 0 0 0 0 10 0 30 % C
% Asp: 10 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % D
% Glu: 30 0 0 0 10 40 0 0 0 0 0 0 40 80 0 % E
% Phe: 0 0 0 70 0 10 10 0 80 20 0 0 0 0 0 % F
% Gly: 0 0 20 0 0 0 0 0 0 0 10 10 0 0 10 % G
% His: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 10 0 0 0 0 0 0 0 10 0 0 % K
% Leu: 0 0 0 10 0 30 20 0 0 10 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % M
% Asn: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 40 % N
% Pro: 0 70 30 0 0 0 0 0 0 0 10 0 30 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 30 0 0 0 50 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 20 50 0 0 0 10 70 10 0 0 70 0 0 10 % S
% Thr: 10 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % T
% Val: 10 0 0 0 0 10 40 0 10 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 0 10 10 0 50 70 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _